Custom Synthesis of complex molecules is our area of expertise
We offer a full range of CDMO services for small molecule APIs and intermediates to global innovators, collaborating at every stage of their NCE programs from concept to commercialization
Our world class infrastructure is capable of handling projects ranging from gram scale to multi-ton volumes
With our experience and our expertise, we have become key partners to our customers in their quest to bring new path-breaking products to market
Cohance’s offerings across the value chain
Proof of Concept
Scale-up
Commercial Supply
Our Journey
of firsts
and milestones
- First company in the world to develop synthetic route for large-scale production of Camptothecin derivatives
- India’s largest player in custom development and manufacturing of high purity electronic chemicals
- Delivered over >125 projects in last 5 years
- Over 15 years of experience in development and manufacturing of complex heterocyclic, chiral aliphatic, acyclic, sugar based and aromatic compounds
- Developed unique platform technologies like cross-coupling chemistry using different catalysts at gram scale to multi kilo scale
- Highly skilled and diverse team including over 25 PhD’s
- High R&D competence including expertise in Carbonylations , Palladium Foray into Coupling Reactions , High potent molecules, LaCl3/LiCl catalysed Alkyl Grignard reactions and Cryogenic, organometallic, pyrophoric reagents & reactions
Efficient Solutions
We innovate and provide novel and efficient routes of synthesis for Regulatory Starting Materials, Advanced Intermediates and APIs with multi-step manufacturing processes
Efficiency is at the heart of everything we do, and we strive to accelerate the time-to-market
We take pride in being trusted partners for innovators with focus on cost efficiencies, consistent quality and on time delivery
Collaborations
Varied Chemical Reaction Capabilities
We have over 30 years of experience in the synthesis of a wide range of structurally diverse chemical entities and have handled complex chemistries such as cryogenic, cross coupling and carbonylation reactions on a large scale
We are among a handful of CDMO players who have demonstrated the ability to scale up molecules from development stage to commercialization
We have invested in engineering know-how as well as technology-transfer & scale up capabilities which are supported with state-of-the-art infrastructure including containment facilities
Manufacturing Capabilities
Customer Centric Project Management
Systematic and customer centric approach to complete project on time and on budget
Dedicated team, continuous communication and tracking to ensure outcomes
Our
Value
Proposition
Our development capabilities include
- Route selection
- Process development and optimization
- Analytical development and validation
- Synthesis of impurities and analytical reference standards
- ICH stability studies, safety and toxicology assessments
- Controlled substances R&D
Our custom manufacturing services include
- Process and analytical validation
- Lab, kilo and pilot scale manufacturing for pre-clinical studies and all phases of clinical trials
- Commercial manufacturing for product launch and in-market supply (from Kg to MT)
- Quality Assurance and Quality Control
- Regulatory support and filings
Delivering
Complex
Molecules
Select Molecules Include
Pharma
ADCs
HPAPIs
Controlled substances
Specialty chemicals
Electronic Chemicals
Personal Care
Photochromic Molecules